Abstract Acanthamoeba spp.are protist pathogens and causative agents of serious infections including keratitis and granulomatous amoebic encephalitis.Its ability to convert into dormant and highly resistant cysts form limits effectiveness of available therapeutic Bedpans agents and presents a pivotal challenge for drug development.During the cyst s
The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss.Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth, the regulatory mechanisms, both cell-intrinsic and collective, which ensure tissue steady-state are Gold Emboss
Abstract Background As the ultimate method for the treatment of osteoarthritis, total knee arthroplasty (TKA) has been widely used in the clinic.Local injection of Bedpans multimodal cocktails, including corticosteroids, is commonly used for pain management after TKA.This meta-analysis aims to systematically evaluate the effect of periarticular inj